Drugs / TSR-033
last change Feb 2025 re-read 9 days ago

TSR-033

also known as encelimab

Monoclonal antibody

Developed for
neoplasm
Investigated by
GlaxoSmithKline · Tesaro, Inc.

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT03250832 Aug 2017 → Jun 2022 neoplasm Tesaro, Inc. Completed No outcome recorded
Comparator or background therapy1 trial
Phase 1 NCT02817633 Background Jul 2016 → Mar 2027 expected neoplasm Tesaro, Inc. Active not recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as TSR-033 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03250832 ↗
1

NCT02817633 ↗

Known as encelimab “CITRINO, a two-part, Phase 1 dose-escalation study, evaluated encelimab (TSR-033; novel anti-LAG-3) monotherapy and in combination in patients with advanced/metastatic solid tumours.” PMID 40016550 ↗ Feb 2025
Modality Monoclonal antibody “TSR-033 is a humanized monoclonal antibody immunoglobulin (Ig) G4.” NCT03250832 ↗