Drugs / Glucopyranosyl Lipid A
last change Dec 2022 re-read 2 minutes ago

Glucopyranosyl Lipid A

also known as GLA
Developed for
food allergy · influenza · primary cutaneous T-cell lymphoma
Investigated by
Access to Advanced Health Institute (AAHI) · Protein Sciences Corporation · Rockefeller University · Sanofi · Yale University

Trials 4 · a red edge is where a trial was stopped

201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03463135 May 2018 → May 2019 food allergy Sanofi Completed No outcome recorded
Phase 1 NCT01864876 Sep 2012 → Dec 2013 Access to Advanced Health Institute (AAHI) Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01147068 Jun 2010 → Oct 2011 influenza Protein Sciences Corporation Completed No outcome recorded
Phase 21 trial
Phase 2 NCT03742804 Jun → Dec 2019 primary cutaneous T-cell lymphoma Yale University Withdrawn No outcome recorded
Also used as a comparator or background therapy in 1 trial
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01154049 Background Mar 2011 → Apr 2014 schistosomiasis Oswaldo Cruz Foundation Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as glucopyranosyl lipid A “The vaccine was formulated with glucopyranosyl lipid A (GLA) adjuvant in an oil-in-water emulsion (SE)” PMID 26571311 Nov 2015
4

“45µg recombinant hemagglutinin and Glucopyranosyl Lipid A 1.0µg in a 2% oil-in-water stable emulsion” NCT01147068

“G100 is composed of glucopyranosyl lipid A (GLA) formulated in a stable emulsion (SE).” NCT03742804

Glucopyranosyl Lipid A (GLA) in an aqueous formulation (AF).” NCT01864876

NCT03463135

Known as GLA “G100 is composed of glucopyranosyl lipid A (GLA) formulated in a stable emulsion (SE).” NCT03742804
2

“Glucopyranosyl Lipid A (GLA)” NCT03463135

NCT01154049

Route Subcutaneous “5 mcg GLA-AF given as one subcutaneous injection.” NCT01864876