Drugs / GIRIPLADIB
last change Nov 2007 re-read 2 minutes ago

GIRIPLADIB

also known as PLA-695

Small molecule targets PLA2G4A via inhibition

Developed for
osteoarthritis, knee
Investigated by
Wyeth is now a wholly owned subsidiary of Pfizer

Trials 3 · a red edge is where a trial was stopped

2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT00440492 Dec 2006 → Nov 2007 rheumatoid arthritis Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded
Phase 1 NCT00366262 Jun 2006 → Mar 2007 Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00396955 Nov 2006 → Nov 2007 osteoarthritis, knee Wyeth is now a wholly owned subsidiary of Pfizer Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as GIRIPLADIB ChEMBL registry synonym — accepted as the source's own label CHEMBL2104969
Known as PLA-695 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00396955
2

NCT00366262

NCT00440492

Action Inhibit “Cytosolic phospholipase A2 inhibitor” CHEMBL2104969
Modality Small molecule CHEMBL2104969
Route Oral “3 oral doses of PLA-695 administered QD” NCT00396955
Target PLA2G4A “Cytosolic phospholipase A2 inhibitor” CHEMBL2104969