Drugs / SIMUROSERTIB
last change Nov 2022 re-read 2 minutes ago

SIMUROSERTIB

also known as TAK-931 · TAK931F

Small molecule targets CDC7 via inhibition

Developed for
colorectal cancer · malignant pancreatic neoplasm · neoplasm · neoplasm of esophagus · neoplastic disease or syndrome · non-small cell lung carcinoma
Investigated by
Millennium Pharmaceuticals, Inc.

Trials 3 · a red edge is where a trial was stopped

20162017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT03708211 Mar → Dec 2019 neoplasm Millennium Pharmaceuticals, Inc. Completed No outcome recorded
Phase 1 NCT02699749 Mar 2016 → Dec 2019 neoplastic disease or syndrome Millennium Pharmaceuticals, Inc. Completed No outcome recorded
Phase 21 trial
Phase 2 NCT03261947 Oct 2017 → Aug 2020 colorectal cancer, malignant pancreatic neoplasm, neoplasm of esophagus, non-small cell lung carcinoma Millennium Pharmaceuticals, Inc. Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as SIMUROSERTIB ChEMBL registry synonym — accepted as the source's own label CHEMBL4297644
Known as TAK-931 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03261947
2

NCT03708211

NCT02699749

Known as TAK931F ChEMBL registry synonym — accepted as the source's own label CHEMBL4297644
Action Inhibit “TAK-931, a cell division cycle 7 (CDC7) inhibitor” NCT02699749
Modality Small molecule CHEMBL4297644
Route Oral “Patients ages ≥20 years received oral TAK-931” PMID 36970056 Nov 2022
Target CDC7 “TAK-931, a cell division cycle 7 (CDC7) inhibitor” NCT02699749