Drugs / AERAS-404

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT02378207 May 2015 → Oct 2016 tuberculosis Aeras Completed No outcome recorded
Phase 1 NCT02420444 Jan 2011 → May 2012 tuberculosis Aeras Completed No outcome recorded
Phase 1 NCT02109874 Dec 2008 → Dec 2010 tuberculosis Aeras Completed No outcome recorded
Phase 1 NCT02074956 May 2008 → Oct 2009 tuberculosis Aeras Completed No outcome recorded
Phase 1 NCT02066428 Nov 2007 → May 2009 tuberculosis Aeras Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT01861730 Jul 2013 → Dec 2017 tuberculosis Aeras Completed No outcome recorded
Phase 21 trial
Phase 2 NCT02075203 Feb 2014 → Aug 2017 tuberculosis Aeras Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as AERAS 404 “This study will complement one ongoing study (NCT02075203) evaluating the prevention of M. Tuberculosis infection using H4:IC31 (also known as AERAS-404).” NCT02378207
7

AERAS 404 (H4:IC31) contains a fusion protein of 2 mycobacterial antigens (Ag85B and TB 10.4) formulated in IC31 adjuvant.” NCT02066428

NCT02420444

NCT02075203

NCT02066428

NCT01861730

NCT02074956

NCT02109874

Known as H4:IC31 “AERAS 404 (H4:IC31) contains a fusion protein of 2 mycobacterial antigens (Ag85B and TB 10.4) formulated in IC31 adjuvant.” NCT02066428
1

NCT02378207

Modality Vaccine “novel TB vaccine candidate, H4:IC31 (AERAS-404)” PMID 28216183 Feb 2017
Route Intramuscular “administered by intramuscular injection” NCT02074956