Drugs / AdCD40L
last change Apr 2017 re-read 3 minutes ago

AdCD40L

targets CD40, CD40LG via activation

Developed for
melanoma · urinary bladder cancer
Investigated by
Uppsala University · Uppsala University Hospital

Trials 2

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT01455259 Sep 2011 → Jan 2016 melanoma Uppsala University Completed No outcome recorded
Phase 1/2 NCT00891748 Nov 2006 → Oct 2009 urinary bladder cancer Uppsala University Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as AdCD40L ClinicalTrials.gov intervention name — accepted as the source's own label NCT01455259 ↗
1

NCT00891748 ↗

Action Activate “Stimulation of the CD40 pathway to initiate anti-tumor immunity is a promising alternative.” PMID 28427434 ↗ Apr 2017
Route Other “is intratumorally injected/treatment.” NCT01455259 ↗
Target CD40LG “Adenovirus vector serotype 5, E1/E3 deletion with human CD40L gene driven by RSV promoter” NCT00891748 ↗