Drugs / ET1402L1-ARTEMIS™2 T cells
last change Dec 2020 re-read 3 minutes ago

ET1402L1-ARTEMIS™2 T cells

also known as ET1402L1-ARTEMIS T cells

Cell therapy targets AFP

Developed for
hepatocellular carcinoma
Investigated by
Aeon Therapeutics (Shanghai) Co., Ltd. · Eureka Therapeutics Inc. · First Affiliated Hospital Xi'an Jiaotong University

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 0 NCT03888859 Dec 2017 → Apr 2019 hepatocellular carcinoma First Affiliated Hospital Xi'an Jiaotong University Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as ET1402L1-ARTEMIS2 T cells “Clinical study to evaluate safety (primary objectives) and efficacy (secondary objective) of ET1402L1-ARTEMIS™2 T cells in patients with alpha fetoprotein positive (AFP+ )...” NCT03888859 ↗
Known as ET1402L1-ARTEMIS T cells “ET1402L1-ARTEMIS™ T cells -IV” NCT03888859 ↗
Modality Cell therapy “Autologous T cells transduced with lentivirus encoding an anti-AFP (ET1402L1) -ARTEMIS™2 expression construct -intravenous (i.v.) arm” NCT03888859 ↗
Route Other “ET1402L1-ARTEMIS™2 T-cells administered through intravenous infusion” NCT03888859 ↗
Target AFP “The molecular target for ET1402L1-ARTEMIS™2 is human leukocyte antigen (HLA) -A02 complexed with a HLA-A02-restricted peptide of alpha fetoprotein (AFP)” NCT03888859 ↗