Drugs / 18F-PF-06445974
last change Dec 2025 re-read 2 minutes ago

18F-PF-06445974

also known as [18F]PF974 · PF-06445974 F-18

Diagnostic / imaging agent targets PDE4B

Investigated by
National Institute of Mental Health (NIMH)

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT07027839 Dec 2025 → Feb 2028 expected alcohol-related disorders National Institute of Mental Health (NIMH) Recruiting No outcome recorded
Phase 1 NCT06795581 Mar 2025 → Dec 2028 expected alcohol-related disorders National Institute of Mental Health (NIMH) Recruiting No outcome recorded
Phase 1 NCT05703685 Jun 2023 → Oct 2028 expected depressive disorder National Institute of Mental Health (NIMH) Recruiting No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as 18F-PF-06445974 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07027839
2

NCT05703685

NCT06795581

Known as [18F]PF974 “Using the PET radioligand \[18F\]PF-06445974 (Hereafter referred to as \[18F\]PF974) to measure PDE4B binding in the brain” NCT07027839
Known as PF-06445974 F-18 ChEMBL registry synonym — accepted as the source's own label CHEMBL5316160
Modality Diagnostic / imaging agent “experimental substance called a radioactive tracer” NCT05703685
Route Intravenous “Injected IV followed by PET scanning” NCT05703685
Target PDE4B “to Image PDE4BNCT05703685