Drugs / Danaparoid Sodium
Danaparoid Sodium
also known as
Danaparoid · Danaparoide de sodio · Danaparoide sodique · ORG 10172 · Orgaran · Sodium danaparoid
targets SERPINC1 via activation
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | ORGARAN | — | 2001-06-26 | fda.gov ↗ |
| Approved | US (FDA) | ORGARAN | — | 1996-12-24 | fda.gov ↗ |
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 3 | NCT03809481 | May 2019 → Jun 2022 | heparin-induced thrombocytopenia | Aspen Global Incorporated | Terminated | No outcome recorded |
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 2 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Danaparoid Sodium | “Drug: Danaparoid Sodium” NCT03809481 ↗ |
| Known as | Danaparoid | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03809481 ↗ |
| Known as | Danaparoide de sodio | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201534 ↗ |
| Known as | Danaparoide sodique | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201534 ↗ |
| Known as | ORG 10172 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201534 ↗ |
| Known as | Orgaran | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201534 ↗ |
| Known as | Sodium danaparoid | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201534 ↗ |
| Action | Activate | “Antithrombin-III activator” CHEMBL1201534 ↗ |
| Action | Inhibit | “inhibits thrombin generation by indirect anti-Xa inhibition and direct inhibition of factor IX activation” NCT03809481 ↗ |
| Route | Intravenous | “Subjects will receive danaparoid via IV infusion for at least 7 days then transition to a VKA.” NCT03809481 ↗ |
| Target | SERPINC1 | “Antithrombin-III activator” CHEMBL1201534 ↗ |