Drugs / HBI-2376
last change Apr 2022 re-read 3 minutes ago

HBI-2376

Developed for
malignant colon neoplasm · malignant pancreatic neoplasm · non-small cell lung carcinoma
Investigated by
HUYABIO International, LLC.

Trials 1

202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05163028 Dec 2021 → Dec 2026 expected malignant colon neoplasm, malignant pancreatic neoplasm, non-small cell lung carcinoma HUYABIO International, LLC. Active not recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2022-04-13 Suzhou Genhouse Bio Co., Ltd. Results 勤浩医药合作伙伴沪亚生物国际在AACR年会公布SHP2抑制剂HBI-2376(GH21)临床前数据 genhousebio.com ↗
此次公布的临床前研究结果显示,在多种KRAS或EGFR突变的CDX/PDX模型中,GH21均表现出比竞品TNO-155和RMC-4550更强的效力。

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as HBI-2376 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05163028 ↗
Action Inhibit “HBI-2376 is a SHP2 Inhibitor” NCT05163028 ↗
Route Oral “HBI-2376 as an oral monotherapy” NCT05163028 ↗