Drugs / RNA anti-CD19 CAR T cells
last change Jun 2018 re-read 3 minutes ago

RNA anti-CD19 CAR T cells

also known as CART19 · RNA CART19

Cell therapy targets CD19 via depletion

Developed for
Hodgkins lymphoma
Investigated by
University of Pennsylvania

Trials 1

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 0 NCT02277522 Oct 2014 → Nov 2016 Hodgkins lymphoma University of Pennsylvania Terminated No outcome recorded Stop: Enrollment

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as RNA anti-CD19 CAR T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT02277522 ↗
Known as CART19 “we used nonviral RNA CART19 cells” PMID 29925499 ↗ Jun 2018
Known as RNA CART19 “we used nonviral RNA CART19 cells” PMID 29925499 ↗ Jun 2018
Action Deplete “eradicating CD19+ B cells within the TME” PMID 29925499 ↗ Jun 2018
Modality Cell therapy “CAR-modified T cells are being investigated in many settings” PMID 29925499 ↗ Jun 2018
Route Intravenous “intravenously administered” NCT02277522 ↗
Target CD19 “using anti-CD19-directed CAR-modified T cells (CART19)” PMID 29925499 ↗ Jun 2018