Drugs / plocabulin
last change Aug 2024 re-read 3 minutes ago

plocabulin

also known as PM060184 · J3.348.355D · Plo · Plocabulina · Plocabuline

Small molecule

Developed for
cancer · colorectal cancer
Investigated by
PharmaMar

Trials 3

20112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT02533674 Dec 2014 → Jul 2019 cancer PharmaMar Completed No outcome recorded
Phase 1 NCT01299636 Jan 2011 → Aug 2015 cancer PharmaMar Completed No outcome recorded
Phase 21 trial
Phase 2 NCT03427268 Jan 2018 → Feb 2019 colorectal cancer PharmaMar Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as plocabulin “Plocabulin (Plo) induces depolymerization of tubulin fibers with disorganization and fragmentation of the microtubule network leading to mitosis.” PMID 39096398 ↗ Aug 2024
Known as J3.348.355D ChEMBL registry synonym — accepted as the source's own label CHEMBL4297636 ↗
Known as Plo “Plocabulin (Plo) induces depolymerization of tubulin fibers with disorganization and fragmentation of the microtubule network leading to mitosis.” PMID 39096398 ↗ Aug 2024
Known as Plocabulina ChEMBL registry synonym — accepted as the source's own label CHEMBL4297636 ↗
Known as Plocabuline ChEMBL registry synonym — accepted as the source's own label CHEMBL4297636 ↗
Known as PM060184 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02533674 ↗
2

NCT03427268 ↗

NCT01299636 ↗

Modality Small molecule — CHEMBL4297636 ↗
Route Intravenous “PM060184 administered intravenously (i.v.)” NCT01299636 ↗