Drugs / DISITERTIDE
last change Dec 2010 re-read 3 minutes ago

DISITERTIDE

Peptide targets TGFB1 via inhibition

Developed for
cutaneous sclerosis
Investigated by
Digna Biotech S.L. · ISDIN

Trials 2

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT00781053 Jul 2008 → Dec 2010 cutaneous sclerosis ISDIN Completed No outcome recorded
Phase 2 NCT00574613 Sep 2007 → Nov 2009 cutaneous sclerosis ISDIN Completed No outcome recorded
Comparator or background therapy1 trial
Phase 1 NCT00656825 Comparator Mar → Jun 2007 — ISDIN Completed No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as DISITERTIDE ChEMBL registry synonym — accepted as the source's own label CHEMBL2108346 ↗
Known as Disitertida ChEMBL registry synonym — accepted as the source's own label CHEMBL2108346 ↗
Known as P144 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00574613 ↗
2

NCT00656825 ↗

NCT00781053 ↗

Known as Peptide 144 “Peptide 144 (P144)is a acetic salt of a 14mer peptide from human TGF-beta1 type III receptor (betaglycan).” NCT00781053 ↗
2

“Peptide 144 (P144) is the acetic salt of a 14mer peptide from human TGF-β1 type III receptor (betaglycan).” NCT00574613 ↗

“Peptide 144 (P144) is the acetic salt of a 14mer peptide from human TGF-β1 type III receptor (betaglycan).” NCT00656825 ↗

Known as Peptide 144 tgf beta-1-inhibitor ChEMBL registry synonym — accepted as the source's own label CHEMBL2108346 ↗
Action Inhibit “P144 TGF-β1-inhibitor has been specifically designed to block the interaction between TGF-β1 and TGF-β1 type III receptor” NCT00574613 ↗
Modality Peptide “Peptide 144 (P144) is the acetic salt of a 14mer peptide” NCT00574613 ↗
Route Topical “topical application of P144” NCT00574613 ↗
Target TGFB1 “P144 TGF-beta1-inhibitor has been specifically designed to block the interaction between TGF-beta1 and TGF-beta1 type III receptor” NCT00781053 ↗