Drugs / PF-06939999
last change Nov 2022 re-read 3 minutes ago

PF-06939999

Small molecule targets PRMT5 via inhibition

Developed for
cancer · metastatic neoplasm
Investigated by
Pfizer

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03854227 Mar 2019 → Apr 2022 cancer, metastatic neoplasm Pfizer Terminated No outcome recorded Stop: Business

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as PF-06939999 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03854227 ↗
Action Inhibit “PF-06939999, a small-molecule inhibitor of protein arginine methyltransferase 5” PMID 36394153 ↗ Nov 2022
Modality Small molecule “PF-06939999, a small-molecule inhibitor of protein arginine methyltransferase 5” PMID 36394153 ↗ Nov 2022
Route Oral “PF-06939999 orally at escalating doses on a continuous basis” NCT03854227 ↗
Target PRMT5 “PF-06939999, a small-molecule inhibitor of protein arginine methyltransferase 5” PMID 36394153 ↗ Nov 2022