Drugs / GSK3050002
last change Apr 2020 re-read 3 minutes ago

GSK3050002

also known as HGS-1035 · KANAB071

Monoclonal antibody targets CCL20

Developed for
autoimmune disease
Investigated by
GlaxoSmithKline · Eisai Inc.

Trials 2

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02671188 Jun 2018 → Aug 2019 autoimmune disease GlaxoSmithKline Withdrawn No outcome recorded
Phase 1 NCT01984047 Jan 2014 → Feb 2015 ulcerative colitis GlaxoSmithKline Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as GSK3050002 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02671188 ↗
1

NCT01984047 ↗

Known as HGS-1035 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297967 ↗
Known as KANAB071 ChEMBL registry synonym — accepted as the source's own label CHEMBL4297967 ↗
Action Inhibit “binds to and neutralizes the action of human CCL20” NCT02671188 ↗
Modality Monoclonal antibody “a humanized IgG1 monoclonal antibody against human CCL20” PMID 32325480 ↗ Apr 2020
Route Intravenous “GSK3050002 is a white to off-white lyophilized powder that will be reconstituted with sterile water for intravenous infusion” NCT01984047 ↗
Target CCL20 “a humanized IgG1 monoclonal antibody against human CCL20” PMID 32325480 ↗ Apr 2020