Drugs / CTB-ACE2
last change Apr 2025 re-read 3 minutes ago

CTB-ACE2

Protein / enzyme biologic

Developed for
COVID-19
Investigated by
University of Pennsylvania

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT05433181 Feb → Apr 2025 COVID-19 University of Pennsylvania Withdrawn No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CTB-ACE2 “CTB-ACE2, with efficient binding to both GM1 and ACE2 receptors, effectively blocks binding of the spike protein and viral entry into human cells.” NCT05433181 ↗
Action Inhibit “effectively blocks binding of the spike protein and viral entry into human cells” NCT05433181 ↗
Modality Protein / enzyme biologic “Angiotensin Converting Enzyme 2 expressed in lettuce chloroplasts” PMID 36314106 ↗ Dec 2022
Route Oral “The IP is formulated as an oral plant powder” NCT05433181 ↗