Drugs / Glycyrrhetinic Acid
last change Jun 2021 re-read 3 minutes ago

Glycyrrhetinic Acid

also known as 18B Glycyrrhetinic acid

targets HSD11B1 via inhibition

Developed for
end stage renal failure · autoimmune thrombocytopenia
Investigated by
Insel Gruppe AG, University Hospital Bern

Trials 1

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT00384384 Aug 2006 → Apr 2007 end stage renal failure Insel Gruppe AG, University Hospital Bern Completed No outcome recorded
Comparator or background therapy1 trial
Phase 4 NCT03998982 Comparator Jun 2019 → Jun 2021 autoimmune thrombocytopenia Shandong University Unknown No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Glycyrrhetinic Acid ClinicalTrials.gov intervention name — accepted as the source's own label NCT03998982 ↗
1

NCT00384384 ↗

Known as 18B Glycyrrhetinic acid “Background: 18B Glycyrrhetinic acid (active compound of Licorice)” NCT00384384 ↗
Action Inhibit “18B Glycyrrhetinic acid is an inhibitor of 11B Hydroxysteroid dehydrogenase type 1” NCT00384384 ↗
Route Oral “comparing oral 18b Glycyrrhetinic acid with placebo” NCT00384384 ↗
Target HSD11B1 “18B Glycyrrhetinic acid is an inhibitor of 11B Hydroxysteroid dehydrogenase type 1” NCT00384384 ↗