Drugs / Narlumosbart
last change Feb 2025 re-read 2 minutes ago

Narlumosbart

Monoclonal antibody targets TNFSF11 via inhibition

Developed for
bone giant cell tumor · disease of bone structure · non-small cell lung carcinoma · plasma cell myeloma
Investigated by
Shanghai JMT-Bio Inc. · Fudan University · RenJi Hospital

Trials 3 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 21 trial
Phase 2 NCT06738160 Feb 2025 → Jan 2027 expected non-small cell lung carcinoma Fudan University Recruiting No outcome recorded
Phase 32 trials
Phase 3 NCT06314698 Apr → Dec 2024 overdue disease of bone structure, plasma cell myeloma RenJi Hospital Not yet recruiting No outcome recorded
Phase 3 NCT05813665 Apr 2023 → Jun 2028 expected bone giant cell tumor Shanghai JMT-Bio Inc. Not yet recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as Narlumosbart ClinicalTrials.gov intervention name — accepted as the source's own label NCT05813665
2

NCT06738160

NCT06314698

Action Inhibit “Narlumosbart is a recombinant, fully human, anti-receptor activator of nuclear factor kappa-Β ligand (RANKL) IgG4 monoclonal antibody.” NCT06314698
Modality Monoclonal antibody “Narlumosbart is a recombinant, fully human, anti-receptor activator of nuclear factor kappa-Β ligand (RANKL) IgG4 monoclonal antibody.” NCT06314698
Route Subcutaneous “Administered by subcutaneous injection once every 4 weeks.” NCT06314698
Target TNFSF11 “Narlumosbart is a recombinant, fully human, anti-receptor activator of nuclear factor kappa-Β ligand (RANKL) IgG4 monoclonal antibody.” NCT06314698