Drugs / BI 811283
last change Nov 2018 re-read 3 minutes ago

BI 811283

targets AURKB via inhibition

Developed for
acute myeloid leukemia · neoplasm
Investigated by
Boehringer Ingelheim

Trials 2

200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00701324 Jun 2007 → May 2011 neoplasm Boehringer Ingelheim Completed No outcome recorded
Phase 21 trial
Phase 2 NCT00632749 May 2008 → Mar 2014 acute myeloid leukemia Boehringer Ingelheim Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as BI 811283 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00632749 ↗
1

NCT00701324 ↗

Action Inhibit “Serine/threonine-protein kinase Aurora-B inhibitor” CHEMBL3545395 ↗
1

“Aurora B kinase inhibitor BI 811283” PMID 30450591 ↗ Nov 2018

Route Intravenous “BI 811283 (24 hours i.v.c.i.) on day 1 and 15 of a 4-week treatment cycle” NCT00632749 ↗
Target AURKB “Serine/threonine-protein kinase Aurora-B inhibitor” CHEMBL3545395 ↗