Drugs / DCR-MYC
last change Nov 2016 re-read 3 minutes ago

DCR-MYC

Small interfering RNA (siRNA) targets MYC via inhibition

Developed for
hepatocellular carcinoma · non-Hodgkin lymphoma · pancreatic neuroendocrine tumor · plasma cell myeloma
Investigated by
Dicerna Pharmaceuticals, Inc.

Trials 2

20142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02110563 Apr 2014 → Oct 2016 non-Hodgkin lymphoma, pancreatic neuroendocrine tumor, plasma cell myeloma Dicerna Pharmaceuticals, Inc. Terminated No outcome recorded Stop: Business
Phase 1/21 trial
Phase 1/2 NCT02314052 Jan 2015 → Oct 2016 hepatocellular carcinoma Dicerna Pharmaceuticals, Inc. Terminated No outcome recorded Stop: Business

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as DCR-MYC ClinicalTrials.gov intervention name — accepted as the source's own label NCT02314052 ↗
1

NCT02110563 ↗

Action Inhibit “ability to inhibit MYC” NCT02110563 ↗
Modality Small interfering RNA (siRNA) “Small Inhibitory RNA (siRNA) Oligonucleotide” NCT02110563 ↗
Route Intravenous “administered by 2 hour intravenous (IV) infusion” NCT02110563 ↗
Target MYC “targets the oncogene MYC” NCT02110563 ↗