Drugs / IL13Ralpha2-specific Hinge-optimized 4-1BB-co-stimulatory CAR/Truncated CD19-expressing Autologous TN/MEM Cells
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IL13Ralpha2-specific Hinge-optimized 4-1BB-co-stimulatory CAR/Truncated CD19-expressing Autologous TN/MEM Cells

Cell therapy

Developed for
glioblastoma
Investigated by
Bristol-Myers Squibb · City of Hope Medical Center · Gateway for Cancer Research · National Cancer Institute (NCI)

Trials 1

2020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT04003649 Dec 2019 → Dec 2024 overdue glioblastoma City of Hope Medical Center Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as IL13Ralpha2-specific Hinge-optimized 4-1BB-co-stimulatory CAR/Truncated CD19-expressing Autologous TN/MEM Cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT04003649 ↗
Action Deplete “may attack specific glioma cells and stop them from growing or kill them.” NCT04003649 ↗
Modality Cell therapy “Biological therapies, such as IL13Ralpha2-CAR T cells, use substances made from living organisms” NCT04003649 ↗
Route Other “Given ITV/ITC” NCT04003649 ↗