Drugs / Novel OPV2 candidate 2
last change Dec 2020 re-read 3 minutes ago

Novel OPV2 candidate 2

Vaccine

Developed for
poliomyelitis
Investigated by
Bill and Melinda Gates Foundation · Celerion · Centers for Disease Control and Prevention · PATH · Pierre Van Damme

Trials 1

20192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT04544787 Oct 2018 → Jan 2019 poliomyelitis Pierre Van Damme Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Novel OPV2 candidate 2 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04544787 ↗
Known as nOPV2 candidate 2 “This study is designed to evaluate the safety and immunogenicity of two novel type 2 oral poliovirus vaccine (nOPV2) candidates (nOPV2 candidate 1 and nOPV2 candidate 2) in adults.” NCT04544787 ↗
Known as novel OPV2-c2 “BACKGROUND: Two novel type 2 oral poliovirus vaccine (OPV2) candidates, novel OPV2-c1 and novel OPV2-c2, designed to be more genetically stable than the licensed Sabin...” PMID 33308429 ↗ Dec 2020
Known as S2/S15domV/CpG40 “Live-attenuated serotype-2 poliovirus derived from a modified Sabin type-2 infectious cDNA clone and propagated in Vero cells; candidate 2 (S2/S15domV/CpG40).” NCT04544787 ↗
Modality Vaccine “two novel type 2 oral poliovirus vaccine (nOPV2) candidates” NCT04544787 ↗
Route Oral “administered orally as six drops (0.3 mL total; approximately 10⁶ CCID50).” NCT04544787 ↗