Drugs / DU125530
last change Nov 2012 re-read 3 minutes ago

DU125530

Small molecule targets HTR1A via inhibition

Developed for
major depressive disorder

Trials 0

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Comparator or background therapy1 trial
Phase 2 NCT01119430 Comparator May 2004 → Nov 2007 major depressive disorder Sant Pau Research Institute Terminated No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as DU-125530 “Preclinical and clinical characterization of the selective 5-HT(1A) receptor antagonist DU-125530 for antidepressant treatment.” PMID 22050051 ↗ Nov 2012
1

NCT01119430 ↗

Action Inhibit “DU-125530 is an excellent pre- and post-synaptic 5-HT(1A) receptor antagonist.” PMID 22050051 ↗ Nov 2012
1

“Serotonin 1a (5-HT1a) receptor antagonist” CHEMBL79261 ↗

Modality Small molecule — CHEMBL79261 ↗
Target HTR1A “Serotonin 1a (5-HT1a) receptor antagonist” CHEMBL79261 ↗