Phase 0 1 trial
Phase 0
NCT03719105
Mar 2019 → Dec 2027 expected
aggressive NK-cell leukemia
New York Medical College
Recruiting
No outcome recorded
Phase 1 3 trials
Phase 1
NCT05581030
May 2023 → Oct 2026 expected
acute lymphoblastic leukemia
H. Lee Moffitt Cancer Center and Research Institute
Recruiting
No outcome recorded
Phase 1
NCT05034627
Aug 2022 → Dec 2025 overdue
pancreatic adenocarcinoma
OHSU Knight Cancer Institute
Active not recruiting
No outcome recorded
Phase 1
NCT04953780
Sep 2021 → Feb 2030 expected
acute myeloid leukemia
West Virginia University
Active not recruiting
No outcome recorded
Phase 2 2 trials
Phase 2
NCT06561074
Sep 2025 → Dec 2029 expected
T-cell acute lymphoblastic leukemia , T-lymphoblastic lymphoma
M.D. Anderson Cancer Center
Recruiting
No outcome recorded
Phase 2
NCT02981628
Jun 2017 → Dec 2026 expected
B-cell acute lymphoblastic leukemia
Children's Oncology Group
Active not recruiting
No outcome recorded
Phase 2/3 1 trial
Phase 2/3
NCT04817761
Jul 2021 → Mar 2025
acute lymphoblastic leukemia
Servier
Terminated
No outcome recorded
Stop: Business
Phase 3 2 trials
Phase 3
NCT03007147
Aug 2017 → Jun 2026 overdue
B-cell acute lymphoblastic leukemia , T-cell acute lymphoblastic leukemia , mixed phenotype acute leukemia
Children's Oncology Group
Active not recruiting
No outcome recorded
Phase 3
NCT00671034
Jul 2008 → Feb 2011
B-cell adult acute lymphocytic leukemia , B-cell childhood acute lymphoblastic leukemia
Children's Oncology Group
Completed
No outcome recorded
Comparator or background therapy 15 trials
Phase 1
NCT05292664 Background
Mar 2023 → Jul 2028 expected
acute leukemia of ambiguous lineage , acute lymphoblastic leukemia , lymphoblastic lymphoma , myelodysplastic syndrome +1
Andrew E. Place, MD
Recruiting
No outcome recorded
Phase 1
NCT05326516 Background
Mar 2022 → Jul 2024
acute lymphoblastic leukemia , acute undifferentiated leukemia , mixed phenotype acute leukemia
Syndax Pharmaceuticals
Completed
No outcome recorded
Phase 1/2
NCT05192889 Background
Aug 2022 → Jun 2024 overdue
acute lymphoblastic leukemia
St. Jude Children's Research Hospital
Active not recruiting
No outcome recorded
Phase 2
NCT07636564 Background
Oct 2026 → Apr 2031 expected
B-cell acute lymphoblastic leukemia , T-cell acute lymphoblastic leukemia , acute leukemia of ambiguous lineage
SWOG Cancer Research Network
Not yet recruiting
No outcome recorded
Phase 2
NCT06317662 Background
Jun 2025 → Dec 2028 expected
B-cell acute lymphoblastic leukemia , acute leukemia of ambiguous lineage
National Cancer Institute (NCI)
Recruiting
No outcome recorded
Phase 2
NCT06124157 Background
May 2025 → Dec 2030 expected
B-cell acute lymphoblastic leukemia
National Cancer Institute (NCI)
Recruiting
No outcome recorded
Phase 2
NCT06390319 Background
Dec 2024 → Dec 2027 expected
T-cell acute lymphoblastic leukemia , T-cell non-Hodgkin lymphoma , mixed phenotype acute leukemia
St. Jude Children's Research Hospital
Recruiting
No outcome recorded
Phase 2
NCT06210750 Background
Aug 2024 → Sep 2026
T-cell acute lymphoblastic leukemia , T-lymphoblastic lymphoma
National Cancer Institute (NCI)
Withdrawn
No outcome recorded
Phase 2
NCT05761171 Background
Jan 2024 → Dec 2027 expected
acute lymphoblastic leukemia , mixed phenotype acute leukemia
Children's Oncology Group
Active not recruiting
No outcome recorded
Phase 2
NCT04546399 Background
Dec 2020 → Jun 2028 expected
B-cell acute lymphoblastic leukemia , Down syndrome
National Cancer Institute (NCI)
Recruiting
No outcome recorded
Phase 2
NCT01574274 Comparator
Jun 2012 → Jul 2021 overdue
acute lymphoblastic leukemia , lymphoblastic lymphoma
Dana-Farber Cancer Institute
Active not recruiting
No outcome recorded
Phase 2/3
NCT07072585 Background
Aug 2026 → Sep 2035 expected
T-cell acute lymphoblastic leukemia , T-lymphoblastic lymphoma
Children's Oncology Group
Not yet recruiting
No outcome recorded
Phase 2/3
NCT03117751 Background
Mar 2017 → Sep 2026 overdue
lymphoblastic leukemia, acute, with lymphomatous features
St. Jude Children's Research Hospital
Active not recruiting
No outcome recorded
Phase 3
NCT05602194 Background
Aug 2023 → Sep 2026 overdue
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) , B-lymphoblastic leukemia/lymphoma, BCR-ABL1–like , T-cell acute lymphoblastic leukemia , lymphoblastic lymphoma +1
Children's Oncology Group
Active not recruiting
No outcome recorded
Phase 3
NCT03959085 Background
Oct 2019 → Mar 2032 expected
B-cell acute lymphoblastic leukemia , central nervous system leukemia , lymphoblastic lymphoma , mixed phenotype acute leukemia +1
Children's Oncology Group
Recruiting
No outcome recorded
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