Drugs / Tiapride
Tiapride
also known as
Gramalil · Italprid · Luxoben · NSC-758225 · Sereprile · Tiaprida · Tiapridal · Tiapride hcl · +2 more
Small molecule targets DRD2, DRD3 via inhibition
Trials 2
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 32 trials | ||||||
| Phase 3 | NCT02374567 | Jan 2015 → Jun 2017 | anxiety disorder, dementia, depressive disorder, schizophrenia +1 | Hannover Medical School | Terminated | No outcome recorded |
| Phase 3 | NCT01765829 | Nov 2012 → Nov 2015 | psychotic disorder | Fundación Pública Andaluza Progreso y Salud | Unknown | No outcome recorded |
| Comparator or background therapy2 trials | ||||||
| Phase 3 | NCT00632645 Comparator | Apr 2009 → Apr 2017 | Huntington disease | Assistance Publique - Hôpitaux de Paris | Completed | No outcome recorded |
| Phase 3 | NCT01501695 Comparator | Jan 2008 → Nov 2010 | Tourette syndrome, chronic tic disorder | Tasly Pharmaceuticals, Inc. | Completed | Met primary |
Evidence & citations 16 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Tiapride | “Drugs: Aripiprazole, Olanzapine, Zuclopenthixol, Clotiapine, Flupentixol, Risperidone, Sulpiride, Trifluoperazine, Haloperidol, Quetiapine, Paliperidone, Chlorpromazine,...” NCT01765829 ↗ |
| Known as | Gramalil | ChEMBL registry synonym — accepted as the source's own label CHEMBL84158 ↗ |
| Known as | Italprid | ChEMBL registry synonym — accepted as the source's own label CHEMBL84158 ↗ |
| Known as | Luxoben | ChEMBL registry synonym — accepted as the source's own label CHEMBL84158 ↗ |
| Known as | NSC-758225 | ChEMBL registry synonym — accepted as the source's own label CHEMBL84158 ↗ |
| Known as | Sereprile | ChEMBL registry synonym — accepted as the source's own label CHEMBL84158 ↗ |
| Known as | Tiaprida | ChEMBL registry synonym — accepted as the source's own label CHEMBL84158 ↗ |
| Known as | Tiapridal | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00632645 ↗ |
| Known as | Tiapride hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL84158 ↗ |
| Known as | TIAPRIDE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL84158 ↗ |
| Known as | Tiapridex | ChEMBL registry synonym — accepted as the source's own label CHEMBL84158 ↗ |
| Action | Inhibit | “Dopamine D2 receptor antagonist” CHEMBL84158 ↗1“Dopamine D3 receptor antagonist” CHEMBL84158 ↗ |
| Modality | Small molecule | — CHEMBL84158 ↗ |
| Route | Oral | “Tiapridal (Tiapride), tabs 100 mg / from 300 to 800 mg per day” NCT00632645 ↗ |
| Target | DRD2 | “Dopamine D2 receptor antagonist” CHEMBL84158 ↗ |
| Target | DRD3 | “Dopamine D3 receptor antagonist” CHEMBL84158 ↗ |