Drugs / allogeneic lymphocytes
last change Aug 2007 re-read 3 minutes ago

allogeneic lymphocytes

also known as allogeneic T lymphocytes

Cell therapy

Developed for
breast cancer · melanoma
Investigated by
National Cancer Institute (NCI) · National Heart, Lung, and Blood Institute (NHLBI)

Trials 2

19992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/21 trial
Phase 1/2 NCT00003552 Jan 1999 → Oct 2002 melanoma National Heart, Lung, and Blood Institute (NHLBI) Terminated No outcome recorded
Phase 21 trial
Phase 2 NCT00020176 Jun 2000 → Aug 2007 breast cancer National Cancer Institute (NCI) Completed No outcome recorded
Comparator or background therapy1 trial
Phase 2 NCT00110058 Background Feb 2005 → Jul 2006 leukemia Fred Hutchinson Cancer Center Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as allogeneic lymphocytes ClinicalTrials.gov intervention name — accepted as the source's own label NCT00020176 ↗
2

NCT00110058 ↗

NCT00003552 ↗

Known as allogeneic T lymphocytes “Allogeneic T lymphocytes can induce regression of metastatic breast cancer through an immune-mediated graft-versus-tumor (GVT) effect” PMID 15314059 ↗ Aug 2004
Modality Cell therapy “allogeneic T-cell infusion as adoptive immunotherapy” NCT00003552 ↗
Route Intravenous “receive donor lymphocytes IV on days 42, 70, and 98” NCT00020176 ↗