Drugs / VES001
last change Oct 2025 re-read 3 minutes ago

VES001

Developed for
frontotemporal dementia
Investigated by
Mads Kjolby · Vesper Biotechnologies ApS

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT06705192 Dec 2024 → Aug 2025 frontotemporal dementia Mads Kjolby Completed No outcome recorded
Phase 1 NCT06226064 Oct 2023 → Jul 2024 frontotemporal dementia Vesper Biotechnologies ApS Completed No outcome recorded

News releases announcing trial results or a regulatory action · 3

DateIssuerRelease
2025-10-01 Vesper Biotechnologies ApS Results VESPER BIO ANNOUNCES POSITIVE PHASE IB/IIA TOPLINE RESULTS FOR LEAD CANDIDATE VES001 FOR FRONTOTEMPORAL DEGENERATION vesperbio.com ↗
2024-09-01 Vesper Biotechnologies ApS Results VESPER BIO ANNOUNCES SUCCESSFUL PHASE I STUDY FOR POTENTIALLY DISEASE-MODIFYING TREATMENT FOR FRONTOTEMPORAL DEMENTIA. vesperbio.com ↗
2024-05-01 Vesper Biotechnologies ApS Results VESPER BIO ANNOUNCES COMPLETION OF SINGLE ASCENDING DOSE STAGE IN TRIAL OF ITS LEAD CANDIDATE VES001. vesperbio.com ↗
Data returned from this study (NCT06226064) demonstrate the safety and tolerability of VES001 across the full range of doses tested and show it has excellent pharmacokinetics and distribution to relevant parts of the brain.

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as VES001 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06705192 ↗
1

NCT06226064 ↗

Route Oral “VES001 is an oral, blood brain barrier penetrating ligand of sortilin.” NCT06226064 ↗