Drugs / DERENOFYLLINE
last change Jan 2010 re-read 3 minutes ago

DERENOFYLLINE

also known as SLV320 · Derenofilina

Small molecule targets ADORA1 via inhibition

Developed for
cardio-renal syndrome · congestive heart failure
Investigated by
Solvay Pharmaceuticals

Trials 2

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00744341 Feb 2009 → Jan 2010 cardio-renal syndrome Solvay Pharmaceuticals Terminated No outcome recorded Stop: Business
Phase 2 NCT00160134 Jan 2005 → ? congestive heart failure Solvay Pharmaceuticals Completed No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as DERENOFYLLINE ChEMBL registry synonym — accepted as the source's own label CHEMBL592435 ↗
Known as Derenofilina ChEMBL registry synonym — accepted as the source's own label CHEMBL592435 ↗
Known as SLV320 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00744341 ↗
1

NCT00160134 ↗

Action Inhibit “an adenosine A1 receptor antagonist” PMID 19919976 ↗ Sep 2009
1

“Adenosine A1 receptor antagonist” CHEMBL592435 ↗

Modality Small molecule — CHEMBL592435 ↗
Route Intravenous “iv SLV320” NCT00160134 ↗
Target ADORA1 “Adenosine A1 receptor antagonist” CHEMBL592435 ↗