Drugs / Triplex
last change Jun 2026 re-read 2 minutes ago

Triplex

Vaccine

Developed for
cytomegalovirus infection
Investigated by
City of Hope Medical Center · National Cancer Institute (NCI) · Diavax Biosciences

Trials 2 · a red edge is where a trial was stopped

20162017201820192020202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT04060277 Nov 2019 → Jun 2023 overdue Hodgkins lymphoma, acute myeloid leukemia, chronic lymphocytic leukemia/small lymphocytic lymphoma, leukemia, myeloid, accelerated-phase +3 City of Hope Medical Center Active not recruiting No outcome recorded
Phase 2 NCT02506933 Dec 2015 → Jan 2018 overdue B-cell chronic lymphocytic leukemia, Hodgkins lymphoma, acute myeloid leukemia, cytomegalovirus infection +5 City of Hope Medical Center Active not recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Triplex “The Triplex vaccine is made up of 3 small pieces of CMV deoxyribonucleic acid (DNA) (the chemical form of genes) placed into a weakened virus called modified vaccinia Ankara (MVA)” NCT04060277
1

Triplex is a recombinant attenuated poxvirus (modified vaccinia Ankara) expressing immunodominant CMV antigens.” PMID 32040960 Feb 2020

Modality Vaccine “Triplex vaccineNCT04060277
Route Intramuscular Intramuscular injections of Triplex or placebo were given on days 28 and 56 after HCT.” PMID 32040960 Feb 2020