Drugs / SAR405838
last change Mar 2018 re-read 9 days ago

SAR405838

also known as MI-773 · MI-773 (SAR405838) · MI-77301

Small molecule targets MDM2 via inhibition

Developed for
cancer
Investigated by
Sanofi · Merck KGaA, Darmstadt, Germany

Trials 2

201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01985191 Nov 2013 → Feb 2016 cancer Sanofi Completed No outcome recorded
Phase 1 NCT01636479 Jul 2012 → Mar 2018 cancer Sanofi Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as SAR405838 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01985191 ↗
1

NCT01636479 ↗

Known as MI-773 ChEMBL registry synonym — accepted as the source's own label CHEMBL2381408 ↗
Known as MI-773 (SAR405838) ChEMBL registry synonym — accepted as the source's own label CHEMBL2381408 ↗
Known as MI-77301 ChEMBL registry synonym — accepted as the source's own label CHEMBL2381408 ↗
Action Inhibit “SAR405838, an HDM2 inhibitor” PMID 28324749 ↗ Mar 2017
Modality Small molecule — CHEMBL2381408 ↗
Route Oral “Route of administration: Oral” NCT01636479 ↗
Target MDM2 “SAR405838, an HDM2 inhibitor” PMID 28324749 ↗ Mar 2017