Drugs / Tetrahydrozoline
Tetrahydrozoline
also known as
Caltheon · NSC-757339 · Rhinopront · TETRAHYDROZOLINE HYDROCHLORIDE · Tetrizolina · tetryzoline · Tetryzoline hydrochloride · Tyzine · +2 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | TYZINE | — | 1979-11-30 | fda.gov ↗ |
Trials 2 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial | ||||||
| Phase 3 | NCT03198000 | Jun → Jul 2017 | — | Johnson & Johnson Consumer Inc. (J&JCI) | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT05028907 | Nov 2020 → May 2021 | lacrimal apparatus disorder | Sohag University | Completed | No outcome recorded |
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 31 trial | ||||||
| Phase 3 | NCT01380678 Comparator | Jan 2009 → Dec 2012 | pterygium | Khon Kaen University | Unknown | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT01227226 Comparator | Oct 2010 → Mar 2011 | dry eye syndrome | Hom, Milton M., OD, FAAO | Unknown | No outcome recorded |
Evidence & citations 13 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | tetrahydrozoline | “ocular clear liquid. Tetrahydrozoline 0.05%; Glycerin 0.40% 1-2 drops will be instilled as instructed over one day” NCT03198000 ↗1“combination of topical antazoline HCl 0.05% and tetrahydrozoline HCl 0.04%” NCT01380678 ↗ |
| Known as | Caltheon | ChEMBL registry synonym — accepted as the source's own label CHEMBL1266 ↗ |
| Known as | NSC-757339 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1266 ↗ |
| Known as | Rhinopront | ChEMBL registry synonym — accepted as the source's own label CHEMBL1266 ↗ |
| Known as | TETRAHYDROZOLINE HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1266 ↗ |
| Known as | Tetrizolina | ChEMBL registry synonym — accepted as the source's own label CHEMBL1266 ↗ |
| Known as | tetryzoline | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05028907 ↗ |
| Known as | Tetryzoline hydrochloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL1266 ↗ |
| Known as | Tyzine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1266 ↗ |
| Known as | Visine | “Visine artificial tear” NCT01227226 ↗ |
| Known as | Yxin | ChEMBL registry synonym — accepted as the source's own label CHEMBL1266 ↗ |
| Modality | Small molecule | — CHEMBL1266 ↗ |
| Route | Topical | “Instill one drop of artificial tears” NCT01227226 ↗ |