Drugs / GW406381
last change Sep 2007 re-read 3 minutes ago

GW406381

Small molecule targets PTGS2 via inhibition

Developed for
dental pulp disorder · neuralgia · osteoarthritis, knee · rheumatoid arthritis
Investigated by
GlaxoSmithKline

Trials 5

200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT00373243 Oct 2005 → Sep 2006 — GlaxoSmithKline Completed No outcome recorded
Phase 1 NCT00279032 Sep 2003 → ? neuralgia, traumatic neuropathy GlaxoSmithKline Completed No outcome recorded
Phase 33 trials
Phase 3 NCT00113308 Jun 2005 → Sep 2006 rheumatoid arthritis GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00120900 May 2005 → Sep 2007 osteoarthritis, knee GlaxoSmithKline Completed No outcome recorded
Phase 3 NCT00114049 Dec 2004 → Apr 2005 dental pulp disorder GlaxoSmithKline Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as GW406381 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00279032 ↗
4

NCT00120900 ↗

NCT00114049 ↗

NCT00113308 ↗

NCT00373243 ↗

Action Inhibit “Cyclooxygenase-2 inhibitor” CHEMBL364804 ↗
1

“COX-2 Inhibitor” NCT00113308 ↗

Modality Small molecule — CHEMBL364804 ↗
Route Oral “Administered Orally Once Daily” NCT00113308 ↗
Target PTGS2 “Cyclooxygenase-2 inhibitor” CHEMBL364804 ↗