Drugs / MS1819
MS1819
Trials 3
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 23 trials | ||||||
| Phase 2 | NCT04302662 | Jun 2019 → Jun 2021 | cystic fibrosis | AzurRx SAS | Completed | No outcome recorded |
| Phase 2 | NCT03746483 | Jan → Jul 2019 | cystic fibrosis, exocrine pancreatic insufficiency | Entero Therapeutics | Completed | No outcome recorded |
| Phase 2 | NCT03481803 | Jan 2017 → Jun 2018 | chronic pancreatitis | AzurRx SAS | Completed | No outcome recorded |
| Comparator or background therapy1 trial | ||||||
| Phase 2 | NCT04375878 Comparator | Jul 2020 → Apr 2021 | cystic fibrosis, exocrine pancreatic insufficiency | Entero Therapeutics | Completed | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | MS1819 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04375878 ↗ |
| Known as | Adrulipase alfa | ChEMBL registry synonym — accepted as the source's own label CHEMBL4298049 ↗ |
| Known as | Lipase 2 (yarrowia lipolytica) | ChEMBL registry synonym — accepted as the source's own label CHEMBL4298049 ↗ |
| Known as | MS1819 Spray Dried | “The new medication is called MS1819 Spray Dried (MS1819-SD) which is a lipase produced by the LIP2 gene of Yarrowia lipolytica using recombinant DNA technology.” NCT03481803 ↗1“The new medication is called MS1819 spray dried (MS1819-SD) which is a lipase produced by the Lip2 gene of Yarrowia lipolytica using recombinant DNA technology.” NCT04302662 ↗ |
| Known as | MS1819-SD | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04302662 ↗ |
| Action | Restore | “for the compensation of exocrine pancreatic insufficiency” NCT03481803 ↗ |
| Modality | Protein / enzyme biologic | “which is a lipase produced by the LIP2 gene of Yarrowia lipolytica using recombinant DNA technology” NCT03481803 ↗ |
| Route | Oral | “MS1819, an oral” NCT03746483 ↗ |