Drugs / Hu1928-Hu20BB-Long
last change Aug 2023 re-read 3 minutes ago

Hu1928-Hu20BB-Long

Cell therapy

Developed for
B-cell chronic lymphocytic leukemia
Investigated by
National Cancer Institute (NCI)

Trials 1

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PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05797233 Aug 2023 → Dec 2028 expected B-cell chronic lymphocytic leukemia National Cancer Institute (NCI) Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Hu1928-Hu20BB-Long “T -cells expressing this CAR construct, called Hu1928-Hu20BB-Long, can specifically recognize CD19 and CD20-expressing target cells in vitro and eradicate CD19 or...” NCT05797233 ↗
Action Deplete “modified to carry genes (chimeric antigen receptor, or CAR T cells) to kill cancer cells.” NCT05797233 ↗
Modality Cell therapy “T-cells obtained by leukapheresis will be genetically modified to express the Hu1928- Hu20BB-Long CAR construct.” NCT05797233 ↗
Route Intravenous “Their T cells, now modified, will be infused back into their bloodstream through a tube placed in a large vein.” NCT05797233 ↗