Drugs / MK-3655
last change Feb 2025 re-read 3 minutes ago

MK-3655

Monoclonal antibody

Developed for
metabolic dysfunction-associated steatohepatitis
Investigated by
Merck Sharp & Dohme LLC

Trials 1

202120222023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT04583423 Nov 2020 → Apr 2023 metabolic dysfunction-associated steatohepatitis Merck Sharp & Dohme LLC Terminated Missed primary Stop: Business

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as MK-3655 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04583423 ↗
Action Activate “selectively activates the FGFR1c/β-klotho co-receptor complex” PMID 39984821 ↗ Feb 2025
Modality Monoclonal antibody “MK-3655, a monoclonal antibody” PMID 39984821 ↗ Feb 2025
Route Subcutaneous “Participants were randomised 1:1:1:1 to receive MK-3655 50 mg, 100 mg, 300 mg, or matching placebo subcutaneously every 4 weeks” PMID 39984821 ↗ Feb 2025