Drugs / ALEPLASININ
last change Dec 2008 re-read 3 minutes ago

ALEPLASININ

also known as PAZ-417 · Aleplasinina · Aleplasinine

Small molecule targets SERPINE1 via inhibition

Developed for
Alzheimer disease
Investigated by
Wyeth is now a wholly owned subsidiary of Pfizer

Trials 3

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT00739037 Aug → Dec 2008 Alzheimer disease Wyeth is now a wholly owned subsidiary of Pfizer Terminated No outcome recorded
Phase 1 NCT00684710 Apr → Aug 2008 Alzheimer disease Wyeth is now a wholly owned subsidiary of Pfizer Completed No outcome recorded
Phase 1 NCT00663065 Apr → Dec 2008 — Wyeth is now a wholly owned subsidiary of Pfizer Terminated No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 4 sources stand behind the page.

FieldValueCited text
Known as ALEPLASININ ChEMBL registry synonym — accepted as the source's own label CHEMBL325424 ↗
Known as Aleplasinina ChEMBL registry synonym — accepted as the source's own label CHEMBL325424 ↗
Known as Aleplasinine ChEMBL registry synonym — accepted as the source's own label CHEMBL325424 ↗
Known as PAZ-417 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00663065 ↗
2

NCT00739037 ↗

NCT00684710 ↗

Action Inhibit “Plasminogen activator inhibitor-1 inhibitor” CHEMBL325424 ↗
Modality Small molecule — CHEMBL325424 ↗
Route Oral “PAZ-417 Administered Orally” NCT00663065 ↗
Target SERPINE1 “Plasminogen activator inhibitor-1 inhibitor” CHEMBL325424 ↗