Drugs / TCR-transduced T cells
last change Apr 2023 re-read 2 minutes ago

TCR-transduced T cells

also known as TCR-T

Cell therapy

Developed for
epithelial neoplasm · cutaneous melanoma · ocular melanoma
Investigated by
Providence Health & Services · Celldex Therapeutics · National Cancer Institute (NCI) · The Netherlands Cancer Institute

Trials 3 · a red edge is where a trial was stopped

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05349890 Apr 2023 → Apr 2027 expected epithelial neoplasm Providence Health & Services Active not recruiting No outcome recorded
Phase 1 NCT04520711 Feb 2022 → Dec 2026 expected epithelial neoplasm Providence Health & Services Active not recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02654821 Mar 2012 → Oct 2019 cutaneous melanoma, ocular melanoma The Netherlands Cancer Institute Unknown No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as TCR-transduced T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT04520711
2

NCT05349890

NCT02654821

Known as TCR-T “T-cell receptor gene-engineered T cells (TCR-T)” NCT04520711
Modality Cell therapy “adoptive transfer of autologous, TCR transduced T cells” NCT02654821
Route Intravenous “one single intravenous adoptive transfer of transduced T cells” NCT02654821