Drugs / Nordihydroguaiaretic Acid
last change Oct 2011 re-read 3 minutes ago

Nordihydroguaiaretic Acid

also known as NDGA

Small molecule targets IGF1R via inhibition

Developed for
prostate cancer
Investigated by
Insmed Incorporated · University of California, San Francisco

Trials 1

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT00678015 May 2008 → Feb 2011 prostate cancer University of California, San Francisco Terminated No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as Nordihydroguaiaretic Acid ClinicalTrials.gov intervention name — accepted as the source's own label NCT00678015 ↗
Known as NDGA “Nordihydroguaiaretic Acid (NDGA)” NCT00678015 ↗
Action Inhibit “NDGA, a small molecule inhibitor of the IGF-1R” PMID 21971890 ↗ Oct 2011
Modality Small molecule “NDGA, a small molecule inhibitor of the IGF-1R” PMID 21971890 ↗ Oct 2011
Route Oral “NDGA 2000 mg was given orally daily” PMID 21971890 ↗ Oct 2011
Target IGF1R “NDGA, a small molecule inhibitor of the IGF-1R” PMID 21971890 ↗ Oct 2011