Drugs / CR1447
last change Oct 2022 re-read 3 minutes ago

CR1447

Small molecule targets AR, ESR2 via activation

Developed for
breast adenocarcinoma
Investigated by
Swiss Cancer Institute

Trials 1

20172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02067741 Jun 2016 → Aug 2018 breast adenocarcinoma Swiss Cancer Institute Terminated No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CR1447 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02067741 ↗
Action Activate “Estrogen receptor beta agonist” CHEMBL3545092 ↗
1

“Androgen Receptor agonist” CHEMBL3545092 ↗

Action Inhibit “acting as a steroidal aromatase inhibitor (AI)” NCT02067741 ↗
Modality Small molecule “CR1447 (4-hydroxytestosterone [4-OHT]) is a steroidal small molecule” NCT02067741 ↗
Route Other “transdermal CR1447” NCT02067741 ↗
Target AR “Androgen Receptor agonist” CHEMBL3545092 ↗
Target ESR2 “Estrogen receptor beta agonist” CHEMBL3545092 ↗