Drugs / CD68-ET3-LV
last change Dec 2024 re-read 3 minutes ago

CD68-ET3-LV

targets F8 via restoration

Developed for
hemophilia A
Investigated by
Christian Medical College, Vellore, India · Dr. H. Trent Spencer, Professor, Emory University of Medicine, Atlanta Ga, 30322

Trials 1

2023202420252026
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT05265767 Apr 2022 → Jun 2024 hemophilia A Christian Medical College, Vellore, India Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as CD68-ET3-LV “Autologous HSCs were transduced with CD68-ET3-LV - a lentiviral vector including a new F8 transgene (ET3)” PMID 39655790 ↗ Dec 2024
Action Restore “Gene therapy for hemophilia A with the use of lentiviral vector-transduced autologous HSCs resulted in stable factor VIII expression” PMID 39655790 ↗ Dec 2024
Route Intravenous “administered by IV infusion” NCT05265767 ↗
Target F8 “a new F8 transgene (ET3)” PMID 39655790 ↗ Dec 2024