Drugs / RO5028442
last change Oct 2016 re-read 3 minutes ago

RO5028442

Small molecule targets AVPR1A via inhibition

Developed for
autism
Investigated by
Hoffmann-La Roche

Trials 1

2012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT01474278 Dec 2011 → Mar 2013 autism Hoffmann-La Roche Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as RO5028442 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01474278 ↗
Action Inhibit “blockade of the V1a receptor” PMID 27711048 ↗ Oct 2016
Modality Small molecule — CHEMBL3416885 ↗
Route Intravenous “a single 20 mg intravenous dose” PMID 27711048 ↗ Oct 2016
Target AVPR1A “the arginine vasopressin receptor 1A (V1a) antagonist” PMID 27711048 ↗ Oct 2016