Drugs / INO-4212
last change Oct 2018 re-read 9 days ago

INO-4212

Vaccine

Developed for
Ebola hemorrhagic fever
Investigated by
Defense Advanced Research Projects Agency · GeneOne Life Science, Inc. · Inovio Pharmaceuticals

Trials 1

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT02464670 May 2015 → May 2018 Ebola hemorrhagic fever Inovio Pharmaceuticals Completed No outcome recorded

News releases announcing trial results or a regulatory action · 3

DateIssuerRelease
2018-10-15 Inovio Pharmaceuticals Results Inovio’s Ebola Vaccine Provides 100% Protection And Elicits Long-Lasting Immune Responses in Preclinical Studies inovio.com ↗
Inovio Pharmaceuticals, Inc. (NASDAQ:INO) announced today that its Ebola vaccine (INO-4212) provided 100% protection following a challenge with a lethal dose of the Ebola virus in a preclinical study.
2016-08-11 Inovio Pharmaceuticals Results Inovio Pharmaceuticals Expands Positive Phase I Ebola Vaccine Trial to Identify Most Optimal Immunization Regimen inovio.com ↗
Inovio is enrolling 125 subjects in a second stage of its phase I trial of INO-4212 after generating positive initial safety and immune response data in the first set of 75 healthy volunteers.
2016-03-30 Inovio Pharmaceuticals Results Inovio Ebola Vaccine Generates Robust Immune Responses in Humans inovio.com ↗
Inovio Pharmaceuticals, Inc. (NASDAQ:INO) announced today that its Ebola vaccine, INO-4212, was safe, tolerable, and generated strong T cell and antibody responses in its fully enrolled phase I study of 75 healthy subjects.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as INO-4212 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02464670 ↗
Modality Vaccine “This study will test the safety, tolerability, and immunogenicity of the DNA vaccine, INO-4212 and its components INO-4201 and INO-4202 in healthy volunteers.” NCT02464670 ↗
Route Intramuscular “INO-4212 delivered IM followed by Electroporation” NCT02464670 ↗