Drugs / ABT-288
last change Feb 2014 re-read 2 minutes ago

ABT-288

Small molecule targets HRH3 via inhibition

Developed for
Alzheimer disease · schizophrenia
Investigated by
AbbVie · AbbVie

Trials 3 · a red edge is where a trial was stopped

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT00888693 Nov 2008 → Dec 2009 schizophrenia AbbVie Completed No outcome recorded
Phase 22 trials
Phase 2 NCT01077700 Mar 2010 → Jul 2011 AbbVie Completed No outcome recorded
Phase 2 NCT01018875 Dec 2009 → Feb 2011 Alzheimer disease AbbVie Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as ABT-288 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01018875
2

NCT01077700

NCT00888693

Action Inhibit “Histamine H3 receptor antagonist” CHEMBL3545029
1

“histamine-3 receptor antagonist” PMID 24516190 Feb 2014

Modality Small molecule CHEMBL3545029
Route Oral “administered orally once daily for 14 days” NCT00888693
Target HRH3 “Histamine H3 receptor antagonist” CHEMBL3545029