Drugs / Enflurane
Enflurane
also known as
Alyrane · ANESTHETIC COMPOUND NO. 347 · Compound 347 · Efrane · Enflurano · Ethrane · Methylflurether · NSC-115944 · +2 more
Small molecule targets KCNK10, KCNK18, KCNK2, KCNK3, KCNK9 via activation
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | ETHRANE | — | 1972-08-28 | fda.gov ↗ |
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| — | NCT00815269 | Dec 2008 → Dec 2009 | — | Nanjing Medical University | Completed | No outcome recorded |
Evidence & citations 18 cited values
Every value below carries the sentence it was read from. 2 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Enflurane | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00815269 ↗ |
| Known as | Alyrane | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Known as | ANESTHETIC COMPOUND NO. 347 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Known as | Compound 347 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Known as | Efrane | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Known as | Enflurano | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Known as | Ethrane | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Known as | Methylflurether | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Known as | NSC-115944 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Known as | Ohio 347 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Known as | R-E-235CA2 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1257 ↗ |
| Action | Activate | “Potassium channel subfamily K member 10 opener” CHEMBL1257 ↗4“Potassium channel subfamily K member 18 opener” CHEMBL1257 ↗ “Potassium channel subfamily K member 2 opener” CHEMBL1257 ↗ “Potassium channel subfamily K member 9 opener” CHEMBL1257 ↗ “Potassium channel subfamily K member 3 opener” CHEMBL1257 ↗ |
| Modality | Small molecule | — CHEMBL1257 ↗ |
| Target | KCNK10 | “Potassium channel subfamily K member 10 opener” CHEMBL1257 ↗ |
| Target | KCNK18 | “Potassium channel subfamily K member 18 opener” CHEMBL1257 ↗ |
| Target | KCNK2 | “Potassium channel subfamily K member 2 opener” CHEMBL1257 ↗ |
| Target | KCNK3 | “Potassium channel subfamily K member 3 opener” CHEMBL1257 ↗ |
| Target | KCNK9 | “Potassium channel subfamily K member 9 opener” CHEMBL1257 ↗ |