Drugs / T-cell Antigen Presenting Cells expressing truncated CD19
last change Sep 2021 re-read 3 minutes ago

T-cell Antigen Presenting Cells expressing truncated CD19

also known as T-APC

Cell therapy

Developed for
B-cell acute lymphoblastic leukemia
Investigated by
Seattle Children's Hospital

Trials 1

2018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1 NCT03186118 Aug 2017 → Sep 2021 overdue B-cell acute lymphoblastic leukemia Seattle Children's Hospital Active not recruiting No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as T-cell Antigen Presenting Cells expressing truncated CD19 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03186118 ↗
Known as T-APC “T-cell Antigen Presenting Cells expressing truncated CD19 (T-APC)” NCT03186118 ↗
Action Activate “T-APCs capable of activating CD19-specific CAR T cells for proliferation and redistribution to tissue beds where tumor cells of ALL seed” NCT03186118 ↗
Modality Cell therapy “Autologous CD4 and CD8 T cells transduced to express a truncated CD19 (CD19t) Transgene” NCT03186118 ↗