Drugs / Radix Puerariae lobatae
Radix Puerariae lobatae
English name Kudzu Root
also known as
Gegen
Traditional medicine (herbal / TCM) targets CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP2D6 via inhibition
Trials 1
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1 | NCT07823140 | Aug 2022 → Apr 2023 | — | Chinese University of Hong Kong | Completed | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 1 source stands behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Radix Puerariae lobatae | ClinicalTrials.gov intervention name — accepted as the source's own label NCT07823140 ↗ |
| Known as | Gegen | “The purpose of this study is to understand how the traditional herbal medicine kudzu root (Gegen, Radix Puerariae lobatae) affects the activity of drug metabolizing enzymes in...” NCT07823140 ↗ |
| Action | Inhibit | “Preclinical data suggest that Gegen can inhibit CYP enzymes” NCT07823140 ↗ |
| Modality | Traditional medicine (herbal / TCM) | “Gegen (Radix Puerariae lobatae) is a common traditional Chinese herbal medicine.” NCT07823140 ↗ |
| Target | CYP1A2 | “This study evaluated Gegen's effects on six key human CYP isoforms (CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6 and CYP3A).” NCT07823140 ↗ |
| Target | CYP2B6 | “This study evaluated Gegen's effects on six key human CYP isoforms (CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6 and CYP3A).” NCT07823140 ↗ |
| Target | CYP2C19 | “This study evaluated Gegen's effects on six key human CYP isoforms (CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6 and CYP3A).” NCT07823140 ↗ |
| Target | CYP2C9 | “This study evaluated Gegen's effects on six key human CYP isoforms (CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6 and CYP3A).” NCT07823140 ↗ |
| Target | CYP2D6 | “This study evaluated Gegen's effects on six key human CYP isoforms (CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6 and CYP3A).” NCT07823140 ↗ |