Drugs / CS0159

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 15 trials
Phase 1 NCT07429331 Mar 2026 Cascade Pharmaceuticals, Inc Completed No outcome recorded
Phase 1 NCT06888115 Mar → May 2025 primary biliary cholangitis Cascade Pharmaceuticals, Inc Completed No outcome recorded
Phase 1 NCT06098027 Oct → Nov 2023 primary biliary cholangitis Cascade Pharmaceuticals, Inc Completed No outcome recorded
Phase 1 NCT05624294 Dec 2022 → Mar 2023 primary biliary cholangitis Cascade Pharmaceuticals, Inc Completed No outcome recorded
Phase 1 NCT05082779 Oct 2021 → Sep 2022 primary sclerosing cholangitis Cascade Pharmaceuticals, Inc Completed No outcome recorded
Phase 23 trials
Phase 2 NCT05896137 Aug 2023 → Nov 2025 overdue primary sclerosing cholangitis Cascade Pharmaceuticals, Inc Active not recruiting No outcome recorded
Phase 2 NCT05896124 Aug 2023 → Dec 2025 overdue primary biliary cholangitis Cascade Pharmaceuticals, Inc Active not recruiting No outcome recorded
Phase 2 NCT05591079 Feb → Nov 2023 metabolic dysfunction-associated steatohepatitis Cascade Pharmaceuticals, Inc Completed No outcome recorded
Phase 31 trial
Phase 3 NCT07282353 Dec 2025 → Dec 2027 expected primary biliary cholangitis Cascade Pharmaceuticals, Inc Recruiting No outcome recorded
Also used as a comparator or background therapy in 2 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
NCT07570810 Comparator Jun → Nov 2026 expected NAFLD1, obesity disorder, type 2 diabetes mellitus Shanghai Jiao Tong University School of Medicine Not yet recruiting No outcome recorded
NCT06492330 Comparator Jul 2024 → Feb 2025 metabolic dysfunction-associated steatohepatitis, obesity disorder, type 2 diabetes mellitus Shanghai Jiao Tong University School of Medicine Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as CS0159 CS0159 (Linafexor)” NCT05591079
10

NCT06888115

NCT07570810

NCT07282353

NCT05896124

NCT06492330

NCT05896137

NCT05082779

NCT05624294

NCT07429331

NCT06098027

Known as Linafexor ClinicalTrials.gov intervention name — accepted as the source's own label NCT05591079
Action Activate “A novel, selective farnesoid X receptor (FXR) agonist.” NCT07429331
Route Oral Oral QD” NCT05591079