Drugs / Terconazole
Terconazole
also known as
Fungistat · Gyno-terazol · NSC-331942 · Panlomyc · R 42470 · Terazol · Terazol 3 · Terazol 3 suppository · +5 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | TERAZOL 7 | — | 1987-12-31 | fda.gov ↗ |
Trials 4
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT01813162 | Dec 2013 → Dec 2014 | — | CONRAD | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT01867164 | Dec 2007 → Dec 2008 | infective vaginitis | Janssen-Cilag, S.A. | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT02180100 | Aug 2013 → Jun 2014 | vulvovaginal candidiasis | Peking University Shenzhen Hospital | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00803738 | Dec 2002 → Dec 2003 | vulvovaginal candidiasis | Padagis LLC | Completed | No outcome recorded |
| Comparator or background therapy4 trials | ||||||
| Phase 3 | NCT03473418 Comparator | Apr → Oct 2018 | vulvovaginal candidiasis | Assiut University | Unknown | No outcome recorded |
| Phase 3 | NCT02308007 Comparator | Jun 2015 → Jun 2018 | infective vaginitis | Curatek Pharmaceuticals, LLC | Completed | No outcome recorded |
| Phase 3 | NCT02308046 Comparator | Jun 2015 → Jun 2017 | infective vaginitis | Curatek Pharmaceuticals, LLC | Completed | No outcome recorded |
| — | NCT04208555 Comparator | Jan 2020 → Feb 2021 | vulvovaginal candidiasis | Hatem AbuHashim | Unknown | No outcome recorded |
News releases announcing trial results or a regulatory action · 1
| Date | Issuer | Release |
|---|---|---|
| 2006-03-21 | Perrigo Company | Regulatory Perrigo Company Announces Approval For Terconazole Suppositories perrigo.com ↗
The Perrigo Company (NASDAQ: PRGO)(TASE: PRGO) announced today that it has received approval from the U.S. Food and Drug Administration (FDA) to manufacture and market terconazole vaginal suppositories, 80 mg. |
All press releases naming this drug 1 release
| Date | Issuer | Release |
|---|---|---|
| 2006-03-21 | Perrigo Company | Perrigo Company Announces Approval For Terconazole Suppositories perrigo.com ↗ |
Evidence & citations 17 cited values
Every value below carries the sentence it was read from. 10 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Terconazole | “One ovule containing 80 milligram (mg) terconazole, 100 mg clindamycin and 0.5 mg fluocinolone acetonide will be administered vaginally, every 24 hours at night, for 3 days.” NCT01867164 ↗7“Terconazole 0.4% vaginal cream: once a day for seven days. 1 applicator (5 gm) of terconazole cream contains 20 mg terconazole.” NCT01813162 ↗ |
| Known as | Fungistat | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | Gyno-terazol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | NSC-331942 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | Panlomyc | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | R 42470 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | Terazol | “Terazol Vaginal Suppository” NCT00803738 ↗ |
| Known as | Terazol 3 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | Terazol 3 suppository | “Terazol 3 suppository” NCT00803738 ↗ |
| Known as | Terazol 7 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | Terconazol | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | Tercospor | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | Termayazole | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Known as | Triaconazole | ChEMBL registry synonym — accepted as the source's own label CHEMBL1714574 ↗ |
| Action | Inhibit | “inhibits fungal cytochrome P-450-mediated 14 alpha-lanosterol demethylase enzyme” NCT03473418 ↗ |
| Modality | Small molecule | “Terconazole is a new, broad-spectrum, triazole antifungal agent.” PMID 25877666 ↗ Apr 2015 |
| Route | Other | “Terconazole 0.4% vaginal cream: once a day for seven days.” NCT01813162 ↗ |