Drugs / GZ389988
last change Sep 2017 re-read 9 days ago

GZ389988

Small molecule targets NTRK1 via inhibition

Developed for
osteoarthritis
Investigated by
Genzyme, a Sanofi Company

Trials 2

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT02424942 Apr 2015 → Jul 2016 osteoarthritis Genzyme, a Sanofi Company Completed No outcome recorded
Phase 21 trial · 1 met primary
Phase 2 NCT02845271 Jul 2016 → Jun 2017 osteoarthritis Genzyme, a Sanofi Company Completed Met primary

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 3 sources stand behind the page.

FieldValueCited text
Known as GZ389988 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02845271 ↗
1

NCT02424942 ↗

Action Inhibit “Nerve growth factor receptor Trk-A inhibitor” CHEMBL3673452 ↗
1

“the TrkA Inhibitor, GZ389988” NCT02424942 ↗

Modality Small molecule — CHEMBL3673452 ↗
Route Other “Route of administration: intraarticular” NCT02424942 ↗
Target NTRK1 “Nerve growth factor receptor Trk-A inhibitor” CHEMBL3673452 ↗