Drugs / sacubitril/valsartan
last change Jul 2025 re-read 2 minutes ago

sacubitril/valsartan

Developed for
diastolic heart failure
Investigated by
Novartis Pharmaceuticals

Trials 1 · a red edge is where a trial was stopped

2015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 3 NCT01920711 Jul 2014 → Jun 2019 diastolic heart failure Novartis Pharmaceuticals Completed No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2018-08-25 Novartis Pharmaceuticals Novartis announces new data that show Entresto® (sacubitril/valsartan) can be initiated early & safely in hospitalized patients after an acute heart failure episode novartis.com

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as sacubitril/valsartan “This was a multicenter, randomized, double-blind, parallel group, active-controlled, study to evaluate the efficacy and safety of sacubitril/valsartan compared to valsartan, on...” NCT01920711
Action Inhibit “neprilysin inhibition” PMID 39873282 Jul 2025